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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE4A
All Species:
30.3
Human Site:
S650
Identified Species:
47.62
UniProt:
Q14139
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14139
NP_004779.2
1066
122561
S650
A
D
D
I
L
E
T
S
A
D
S
L
E
H
V
Chimpanzee
Pan troglodytes
XP_001161169
1066
122495
S650
A
D
D
I
L
E
T
S
A
D
S
L
E
H
V
Rhesus Macaque
Macaca mulatta
XP_001097812
1067
122494
S650
A
D
D
I
L
E
T
S
A
D
S
L
E
H
V
Dog
Lupus familis
XP_850081
1066
122542
S650
A
D
D
I
L
E
T
S
A
D
S
L
E
H
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES00
1173
133285
Y775
Q
Y
S
P
Q
V
L
Y
E
P
C
T
Q
D
I
Rat
Rattus norvegicus
Q6P7A2
1066
122361
S650
A
E
D
I
L
E
T
S
A
D
S
L
E
H
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026081
1074
123247
S654
A
D
D
I
L
E
T
S
A
D
S
L
E
H
I
Frog
Xenopus laevis
NP_001084506
1072
122544
A652
A
D
E
V
L
E
T
A
A
D
F
L
E
Q
I
Zebra Danio
Brachydanio rerio
XP_001922961
1078
122949
S658
A
D
E
V
L
E
S
S
A
E
S
L
E
H
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609060
993
113046
Y582
G
E
Q
Y
I
N
I
Y
F
S
A
H
D
A
F
Honey Bee
Apis mellifera
XP_393070
965
109934
L561
I
P
E
F
I
I
V
L
M
E
S
Q
Q
R
L
Nematode Worm
Caenorhab. elegans
Q09349
980
113212
L591
I
S
N
G
M
K
L
L
M
E
R
N
A
D
W
Sea Urchin
Strong. purpuratus
XP_786748
942
107668
T582
Y
A
T
S
E
D
V
T
L
L
T
T
P
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LF41
1038
117510
D617
A
L
D
G
V
P
L
D
D
F
M
N
F
I
I
Baker's Yeast
Sacchar. cerevisiae
P54860
961
109887
F558
R
N
P
R
L
G
S
F
V
E
F
T
T
M
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.1
98.6
N.A.
24.6
97
N.A.
N.A.
87.7
79.7
76.7
N.A.
33.1
36.5
22.9
32.7
Protein Similarity:
100
100
98.5
99.4
N.A.
45.2
99
N.A.
N.A.
94.3
90.8
87.4
N.A.
51.3
54.5
42.5
52.2
P-Site Identity:
100
100
100
100
N.A.
0
93.3
N.A.
N.A.
93.3
60
73.3
N.A.
0
6.6
0
0
P-Site Similarity:
100
100
100
100
N.A.
13.3
100
N.A.
N.A.
100
86.6
100
N.A.
26.6
40
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.3
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.9
41.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
60
7
0
0
0
0
0
7
54
0
7
0
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
47
47
0
0
7
0
7
7
47
0
0
7
14
0
% D
% Glu:
0
14
20
0
7
54
0
0
7
27
0
0
54
0
0
% E
% Phe:
0
0
0
7
0
0
0
7
7
7
14
0
7
0
7
% F
% Gly:
7
0
0
14
0
7
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
0
47
0
% H
% Ile:
14
0
0
40
14
7
7
0
0
0
0
0
0
7
27
% I
% Lys:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
7
0
0
60
0
20
14
7
7
0
54
0
0
14
% L
% Met:
0
0
0
0
7
0
0
0
14
0
7
0
0
7
0
% M
% Asn:
0
7
7
0
0
7
0
0
0
0
0
14
0
0
0
% N
% Pro:
0
7
7
7
0
7
0
0
0
7
0
0
7
0
0
% P
% Gln:
7
0
7
0
7
0
0
0
0
0
0
7
14
7
0
% Q
% Arg:
7
0
0
7
0
0
0
0
0
0
7
0
0
7
0
% R
% Ser:
0
7
7
7
0
0
14
47
0
7
54
0
0
7
0
% S
% Thr:
0
0
7
0
0
0
47
7
0
0
7
20
7
0
0
% T
% Val:
0
0
0
14
7
7
14
0
7
0
0
0
0
0
47
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
7
7
0
7
0
0
0
14
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _